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美国Genes&Development杂志发表了中国科学院生物物理研究所许瑞明研究组题为“Structural basis for allosteric,substrate-dependent stimulation of SIRT1 activity by resveratrol”的最新研究论文,报道了他们关于白藜芦醇促进去乙酰化酶SIRT1酶活性作用机制的最新研究进展。人源SIRT1是Sir2(Silent information regulator 2)超蛋白家族的成员之一,它是NAD+依赖型的去乙酰化酶,能够催化组蛋白底物和非组蛋
Genes & Development magazine published the latest research paper titled “Structural basis for allosteric, substrate-dependent stimulation of SIRT1 activity by resveratrol” by the Research Group of Xu Ruiming, Institute of Biophysics, Chinese Academy of Sciences, and reported that their research on resveratrol promotion Recent Progress in the Mechanism of SIRT1 Enzyme Activity. Human SIRT1 is a member of the Sir2 (Silent information regulator 2) super-protein family and is an NAD + -dependent sirtuin that catalyzes both histone substrates and non-histone