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目的:探讨大切口无缝线白内障囊外摘除术(SLIMCE)后泪膜情况。方法:行SLIMCE术眼68例,分别于术前及术后7,14,30,60,90d行症状、泪膜破裂时间(BUT)、基础泪液分泌试验(SⅠt)、角膜荧光素染色(FL)检测。运用结膜印迹细胞学及显微图象分析系统对SLIMCE术区结膜杯状细胞进行记数分析。结果:90d内术眼不适患者较术前增加(5-27,23,19,16,13;2-16,14,8,6,3),术后14d内SⅠt增加(10.1±4.5;15.0±4.7,13.8±5.7),30d内BUT缩短(10.3±2.2;5.5±2.3,7.0±2.4,7.9±2.2),FL增高(0-17,9,5;0-8,3,1),与术前相比有统计学差异(P<0.05)。结论:SLIMCE术后会影响泪膜稳定性。
Objective: To investigate the situation of tear film after large incision sutureless extracapsular cataract extraction (SLIMCE). Methods: Sixty-eight patients underwent SLIMCE, who underwent preoperative and postoperative 7th, 14th, 30th, 60th and 90th days respectively. The symptoms, tear time (BUT), basal tear secretion test (SⅠt), corneal fluorescein staining ) Test. The conjunctival goblet cells were counted by conjunctival imprinting cytology and microscopic image analysis system. Results: The patients with eye discomfort within 90 days were more preoperatively (5-27,23,19,16,13; 2-16,14,8,6,3), SⅠt increased within 14 days after operation (10.1 ± 4.5; 15.0 ± 4.7, ± 13.8 ± 5.7), shortening of BUT within 30 days (10.3 ± 2.2; 5.5 ± 2.3, 7.0 ± 2.4, 7.9 ± 2.2) Compared with the preoperative statistics (P <0.05). Conclusion: SLIMCE surgery will affect tear film stability.