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邻碘马尿酸钠是制备放射性药物~(131)I-邻碘马尿酸钠(OIH)的主要原料,其杂质邻碘苯甲酸(OIB)的含量直接关系到该药物的临床诊断效果。过去一直没有直接分析该杂质的准确方法。本文研究的高效液相色谱法,适于直接分析邻碘马尿酸钠原料中的邻碘苯甲酸含量。该
O-iodohippurate sodium is the main raw material for the preparation of ~ (131) I-o-iodohippurate (OIH). The content of o-iodobenzoic acid (OIB) is directly related to the clinical diagnosis of the drug. There has been no accurate way of analyzing this impurity in the past. The high performance liquid chromatography studied in this paper is suitable for the direct analysis of o-iodobenzoic acid content in o-iodohippurate sodium raw materials. This