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目的比较梅毒酶联免疫吸附试验(TP-ELISA)法和Abbott i2000 Architect化学发光法(syphilis-TP)检测梅毒I期患者结果的灵敏度。方法对180例临床已经确诊为I期梅毒患者的标本,用梅毒酶联免疫吸附试验(TP-ELISA)法和Abbott i2000 Architect化学发光法(syphilis-TP)进行检测。结果 180例标本中syphilis-TP法检测179例阳性,灵敏度99.44%;TP-ELISA检测阳性162例,灵敏度90.00%。结论 syphilis-TP法检测梅毒Ⅰ期患者结果的灵敏度高于TP-ELISA法。
OBJECTIVE: To compare the sensitivity of Syphilis I ELISA in patients with syphilis I by comparing syphilis enzyme-linked immunosorbent assay (TP-ELISA) and Abbott i2000 Architect chemiluminescence (syphilis-TP). Methods A total of 180 patients with clinically confirmed stage I syphilis were tested for syphilis by TP-ELISA and syphilis-TP by Abbott i2000 Architect. Results 179 cases were detected by syphilis-TP method with a sensitivity of 99.44% in 180 samples. 162 cases were positive by TP-ELISA with a sensitivity of 90.00%. Conclusion The sensitivity of syphilis-TP method in detecting stage Ⅰ syphilis patients is higher than that of TP-ELISA.