地方性克汀(Cretin)病是地方性甲状腺肿流行区的多发病、常见病。我国北方山区及我省农业区各县多见。患者身材矮小,体力弱;智能低下,痴笑,常伴有语言听力障碍,重者生活不能自理,故又称地方性呆小症。关于本症的病因学研究,已有一些报导,但由于各作者调查的方法和角度不同,研究的深度和广度的差异,所得结论亦不一致。而从细胞遗传学 Local Cretin (Cretin) disease is endemic goiter prevalence of multiple, common disease. Mountainous areas in northern China and the agricultural areas in our province more common. Patients with short stature, physical weakness; mental retardation, smiles, often accompanied by language impairment, severe cases of life can not take care of themselves, it is also known as endemic small headedness. There have been some reports about the etiology of this disease. However, due to the different methods and angles of the investigators, the differences in the depth and breadth of the research, the conclusions obtained are also inconsistent. And from cytogenetics