Influence of core property on multi-electron process in the collisions of q=6-9 and 11 isocharged sequence ions with Ne is investigated in the keV/u region.The cross-section ratios of double-,triple-,quadruple-and total multi-electron processes to the single electron capture process as well as the partial ratios of different reaction channels to the relevant multi-electron process are measured by using position-sensitive and time-of-flight techniques.The experimental data axe compared with the theoretical predictions including the extended classical over-barrier model,the molecular Columbic barrier model and the semi-empirical scaling law.Results show a core effect on multi-electron process of isocharge ions colliding with Neon,which is consistent with the results of Helium we obtained previously.