从马可波罗出游至1934年,人们只知硒的毒害作用.1943年发表Nelson的研究报告后,人们又一直认为硒是致癌物质.虽然Clayfon及Weisberg等(1956年)已指出,硒有抑癌作用,但直至60～70年代作了大量研究后,才确定了硒的抗癌性能.1957年Schwarz首先证明硒为动物所必需;1958年 Traveling from Marco Polo to Selenium in 1934 was known only for the toxic effects of selenium, and Selenium was also considered a carcinogen after the Nelson study was published in 1943. Although Clayfon and Weisberg et al. (1956) have noted that selenium has tumor suppressor effects , But it was not until the 1960s and 1970s that a large number of studies were made on the anti-cancer properties of selenium. In 1957 Schwarz first proved that selenium is necessary for animals; in 1958