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目的探讨应用5-氨基酮戊酸光动力疗法联合中药治疗面部扁平疣的临床效果。方法回顾性分析2011年5月~2014年1月我院皮肤科收治的123例面部扁平疣患者,应用随机数字分组法分为治疗组和对照组,对照组予以5-氨基酮戊酸光动力梯度疗法,治疗组在对照组的基础上加用中药治疗。结果在治疗2周后治疗组总有效率为95.24%,对照组总有效率为81.67%,两组疗效比较差异具有统计学意义(x~2=5.612,P=0.018);在治疗6周后治疗组总有效率为100%,对照组总有效率为91.67%,两组疗效比较差异具有统计学意义(x~2=5.472,P=0.019);治疗组及对照组复发率分别为3.17%、18.33%,两组疗效比较差异具有统计学意义(P<0.05)。结论 5-氨基酮戊酸光动力疗法联合中药治疗面部扁平疣可缩短疗程,同时可以减少复发率,值得临床借鉴。
Objective To investigate the clinical effect of 5-aminolevulinic acid photodynamic therapy combined with traditional Chinese medicine in the treatment of facial flat warts. Methods A retrospective analysis of 123 cases of facial flat warts admitted to our hospital from May 2011 to January 2014 was made. The patients were divided into treatment group and control group by random number grouping method. The control group was given photodynamic therapy with 5-aminolevulinic acid Gradient therapy, the treatment group in the control group based on the use of traditional Chinese medicine treatment. Results After 2 weeks of treatment, the total effective rate was 95.24% in the treatment group and 81.67% in the control group. The difference between the two groups was statistically significant (x 2 = 5.612, P = 0.018). After 6 weeks of treatment The total effective rate was 100% in the treatment group and 91.67% in the control group. The difference between the two groups was statistically significant (x ~ 2 = 5.472, P = 0.019). The recurrence rates of the treatment group and the control group were 3.17% , 18.33%, the difference between the two groups was statistically significant (P <0.05). Conclusion 5-aminolevulinic acid photodynamic therapy combined with traditional Chinese medicine treatment of facial flat warts can shorten the course of treatment, while reducing the recurrence rate, it is worth learning from.