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目的:了解北京市昌平区健康人群脊髓灰质炎抗体水平。方法:调查昌平区10个村的<1、1～4、5～9、10～14、15～19、20～24、25～29、30～34、35～39、≥40岁健康人群共220人,采用酶联免疫吸附试验(ELISA)测定脊灰中和抗体。结果:Ⅰ、Ⅱ、Ⅲ型脊灰中和抗体阳性率分别为96.36%、96.36%、92.27%;几何平均滴度(GMT)分别为1∶55.02、1∶52.66、1∶42.40。不同户籍、性别、年龄和免疫史间抗体体水平差别无统计学意义。结论:昌平区健康人群脊灰抗体水平保持在较高水平,对脊灰形成了免疫屏障。
Objective: To understand the level of poliomyelitis antibody in healthy population in Changping District of Beijing. Methods: A total of 10 villages in Changping District, <1,1 ~ 4,5 ~ 9, 10 ~ 14, 15 ~ 19, 20 ~ 24, 25 ~ 29, 30 ~ 34, 35 ~ 39, 220 people, the use of enzyme-linked immunosorbent assay (ELISA) determination of polio neutralizing antibodies. Results: The positive rates of neutralizing antibodies of type Ⅰ, Ⅱ and Ⅲ were 96.36%, 96.36% and 92.27%, respectively. The geometric mean titers (GMTs) were 1: 55.02, 1: 52.66 and 1: 42.40, respectively. There was no significant difference in body weight between different hukou, sex, age and immunization history. Conclusion: The level of poliovirus in healthy population in Changping District is kept at a high level, forming an immune barrier to polio.