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以绿原酸、木犀草苷含量,液相指纹图谱相似度为评价指标,考察自然晒干、烘房烘干、微波杀青烘干、滚筒杀青烘干、硫磺熏蒸阴干5种不同产地加工方法对江苏省东海县药材种植基地金银花质量的影响。结果表明不同产地加工方法对金银花药材中绿原酸含量、液相指纹图谱相似度有显著影响,对木犀草苷含量无明显差异。微波杀青烘干、滚筒杀青烘干样品绿原酸含量较高,分别为3.67%,3.39%,液相指纹图谱相似度分别为0.815,0.793;烘房烘干、硫磺熏蒸阴干样品绿原酸质量分数分别为2.87%,2.53%,液相指纹图谱相似度分别为0.964,0.765;晒干样品绿原酸质量分数最低为1.92%,液相指纹图谱相似度为0.940。根据研究结果,同时结合江苏康缘药业股份有限公司金银花药材内控标准,东海县种植基地金银花最佳加工方法为烘房烘干法,该研究为江苏省东海县药材基地金银花产地加工方法的确定提供了理论依据。
Using chlorogenic acid, luteolin content and similarity of liquid chromatographic fingerprints as evaluation indexes, the processing methods of natural drying, drying oven drying, microwave drying, drying cylinder drying, sulfur fumigation and drying were studied. The Effect of Honeysuckle Quality in Medicinal Planting Base in Donghai County of Jiangsu Province. The results showed that the processing methods of different origins had a significant effect on the similarity of chlorogenic acid content and liquid-phase fingerprint in the honeysuckle, and there was no significant difference in the content of luteolin. The results showed that the content of chlorogenic acid in dried samples was 3.67% and 3.39%, respectively, and the similarities of liquid fingerprint were 0.815 and 0.793 respectively. The drying chlorogenic acid samples The scores were 2.87% and 2.53%, respectively, and the similarities of liquid fingerprint were 0.964 and 0.765 respectively. The lowest chlorogenic acid content of dried samples was 1.92% and the similarity of liquid fingerprint was 0.940. According to the results of the study, combined with the honeysuckle medicine internal control standard of Jiangsu Kang Yuan Pharmaceutical Co., Ltd., the best processing method of honeysuckle in the planting base of Donghai County was drying room drying method. The research was to determine the processing method of the honeysuckle origin in the medicinal material base of Donghai County, Jiangsu Province Provided a theoretical basis.