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用微量热法测定了大肠杆菌在四种金属离子化合物作用下的生长代谢热谱。计算了大肠杆菌在指数生长期的生长速率常数ｋ、传代时间Ｇ、生长抑制率Ｉ和发热量Ｑ等参数；建立了热谱信息参量之间的关系，定量地讨论了金属离子化合物对大肠杆菌生长代谢的抑制，并发现可用Ｐｍａｘ和ｔｒ表征大肠杆菌和生长代谢的化合物的抗菌活性。
The calorimetry of Escherichia coli under the action of four metal ion compounds was determined by microcalorimetry. The growth rate constants k, the passage time G, the growth inhibition rate I and the calorific value Q of Escherichia coli in the exponential growth phase were calculated. The relationship between the parameters of the hyperspectral information was established and the effects of the metal ions on Escherichia coli Inhibition of growth metabolism and found that Pmax and tr can be used to characterize the antibacterial activity of E. coli and the compounds that grow metabolism.