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HBsAg携带者有感染δ因子的高度危险性。δ因子高度致病,可引起急、慢性肝病。δ因子仅能在急性肝炎血清中检出;在慢性肝炎可能在肝组织中检出,而在血清中只能检测到δ抗体。晚近研究提示δ因子是引起无症状HBsAg携带者发生暴发性肝炎的一个因素,δ因子也与HBsAg阳性慢性肝病患者的严重感染有关。作者报道3例有HBsAg阳性慢性肝病史的患者,因病情突然恶化而死亡。曾检测此3例患者血清中的乙型肝炎病毒标记和δ因子。3例均为男性患者,入院时有黄疸。携带HBsAg至少2年,伴丙氨
HBsAg carriers have a high risk of acquiring a delta factor. δ-factor highly pathogenic, can cause acute and chronic liver disease. The delta factor can only be detected in acute hepatitis serum; in chronic hepatitis it is possible to detect it in liver tissue, whereas only delta antibody in serum. Recent studies suggest that delta-factor is a factor that causes fulminant hepatitis in asymptomatic HBsAg carriers, and delta-factor is also associated with severe infection in patients with HBsAg-positive chronic liver disease. The authors report that 3 patients who had a history of HBsAg-positive chronic liver disease died of a sudden deterioration in their condition. Hepatitis B virus markers and delta-factor in the sera of these 3 patients were tested. 3 cases were male patients, admitted to jaundice. Carry HBsAg for at least 2 years, with alanine