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作者对各类型肝病50例(包括急性肝炎22例和慢性肝病28例)血清检测抗-HGV和HCV-RNA,分别采用第二代EIA和PCR法。结果表明:抗-HCV阳性者HCV-RNA阳性率达64％(16/25),在慢性肝病达100％(13/13)。HCV-RNA阳性者抗-HCV阳性率达84.2％。在慢性肝病达92.9％(13/14);而抗-HCV阴性者中HCV-RNA阳性率仅为12％(3/25)。因此两者的符合率较高,说明抗-HCV阳性大多数反映HCV现感染,可以应用于HCV感染的诊断,特别是对于慢性肝病患者。
The authors tested serum anti-HGV and HCV-RNA in 50 cases of various types of liver disease (including 22 cases of acute hepatitis and 28 cases of chronic liver disease) by second-generation EIA and PCR. The results showed that the anti-HCV positive HCV-RNA positive rate was 64% (16/25), chronic liver disease was 100% (13/13). HCV-RNA-positive anti-HCV positive rate of 84.2%. 92.9% (13/14) of patients with chronic liver disease, and only 12% (3/25) of HCV-RNA positive patients with anti-HCV negative disease. Therefore, the coincidence rate of the two is high, indicating that the majority of anti-HCV positive HCV infection can be applied to the diagnosis of HCV infection, especially in patients with chronic liver disease.