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根据１９９１年～１９９２年中日联合调查小组在碘缺乏病区吉林省吉林市丰满区青山村，非病区吉林省通榆县四井子乡的调查结果，对病区４６２例和非病区２０６例１岁～１８岁年龄段人群甲状腺体积与生长发育的关系进行分析研究，发现供碘后缺碘地区未成年人群甲状腺体积略大于非缺碘地区，但都处于正常范围，而且，无论病区还是非病区，人群甲状腺体积的变化与年龄增长呈正相关，并且有明显的阶段性变化。１０岁之前甲状腺增长较平稳，１１岁～１６岁甲状腺体积增大幅度明显高于其它年龄段。这与人体正常发育第二突增相对应。
According to the survey results of the 1991-1992 joint investigation team between Sichuan and Jilin in Fengning District of Ji’nan City, Ji’nan Province, Jilin Province, in Iodine-Deficient Disease Area, 462 cases of ward and 206 cases of non-ward For example, the relationship between the thyroid volume and the growth and development of people aged from 1 to 18 was analyzed. The results showed that the thyroid volume in the iodine-deficient area was slightly larger than that in the non-iodine-deficient area, but both were in the normal range. Or non-ward, the crowd of thyroid volume changes with age was positively correlated, and there are obvious stages of change. Before the age of 10 thyroid growth more stable, 11-year-old 16-year-old thyroid volume increased significantly higher than other age groups. This corresponds to the second normal population development.