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2002年,美国肾脏基金会(NKF)成立了“改善肾脏病预后的初步行动(K/DOQI)”的学术组织,该组织颁布了慢性肾脏病(CKD)的定义和分类标准,根据CKD病情的严重程度,将其分为5期。国际性组织“肾脏疾病:改善全球预后(KDIGO)”成立后,进一步制订CKD治疗指南,以阻止CKD患者急剧增多的趋势。世界范围内透析患者增多是不可改变的事实,但是,为了延缓CKD患者向终末期肾衰竭进展,必须根据CKD治疗指南,采取早期干预措施。据报道,肾功能减退是CKD患者出现心血管意外和不良生命预后的独立危险因素,在针对CKD的防治措施中,处理肾衰竭和心血管意外都很重要。近年来,迅速建立了针对CKD的国际性协调工作机制。在日本,终末期肾衰竭的发病率居世界第3位,患病率居世界第1位,2005年2月,日本肾脏学会成立了处理CKD的2级专业委员会,陆续开展有关CKD的流行病学调查研究。2005年在“日本肾脏周”期间,公布了有关日本CKD流行病学调查的中期报告。
In 2002, the National Kidney Foundation (NKF) set up an academic organization called “Initial Initiative to Improve the Prognosis of Kidney Disease (K / DOQI)”, which enacted the definition and classification of chronic kidney disease (CKD) Severity, divided into 5 phases. The international organization “Kidney disease: improving the global prognosis (KDIGO)” was established, the further development of CKD treatment guidelines to prevent the rapid increase in the trend of CKD patients. The increase in dialysis patients worldwide is an unchangeable fact, however. To delay the progression of CKD to end-stage renal failure, early interventions must be taken based on CKD guidelines. Renal dysfunction is reported to be an independent risk factor for cardiovascular accidents and poor life outcomes in patients with CKD, and renal failure and cardiovascular accidents are important in the management of CKD. In recent years, an international coordination mechanism for CKD has been rapidly established. In Japan, the incidence of end-stage renal failure ranks the third in the world with the highest prevalence in the world. In February 2005, the Japan Society of Nephrology established a second-level professional committee to handle CKD and gradually started the epidemic of CKD Study and research. During the “Kidney Week of Japan” in 2005, an interim report on the epidemiological investigation of CKD in Japan was published.