胎儿宫内发育迟缓 (ＩＵＧＲ)使围生儿病率和病死率显著增高 ,影响患儿儿童期与青春期的智力及体格发育 ,增加成年后发生缺血性心脏病、高血压和糖尿病的危险性。因此 ,预防和减少ＩＵＧＲ的发生对改善围生儿预后、提高人口素质具有重要意义。ＩＵＧＲ的病因复杂 ,6 0 %以上原 Intrauterine growth retardation (IUGR) significantly increases perinatal morbidity and mortality, affects mental and physical development in childhood and adolescence, and increases the risk of ischemic heart disease, hypertension, and diabetes in adulthood . Therefore, to prevent and reduce the incidence of IUGR to improve perinatal prognosis and improve the quality of population is of great significance. The etiology of IUGR is complex, with more than 60% of the original