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目的 通过红细胞免疫功能测定和分析 ,了解大肠癌红细胞免疫功能状况 ,探讨其临床意义。方法 经病理证实大肠癌住院患者 6 8例、正常对照 6 5例抽取外周血 2ml,测定RBC -C3b、RBC -Ic、RFER、RFIR、NTERT ,并运用SPSS统计软件包进行统计比较和相关分析。结果 大肠癌患者RBC -C3b、RFER和NTERT低于正常对照 ,RBC -I、RFIR高于正常对照。大肠癌RBC -C3b、NTERT、RFER、RFIR、RBC -Ic之间存在相关性。结论 大肠癌红细胞免疫功能低下 ,其测定可作为机体免疫功能变化的客观指标 ,在大肠癌辅助诊断、疗效观察、病情监测和预后判断等方面有临床价值。
Objective To understand the status of red blood cell immune function in colorectal cancer through the determination and analysis of red cell immune function, and to explore its clinical significance. Methods Pathologically confirmed 64 inpatients with colorectal cancer and 62 normal controls. Peripheral blood was drawn 2ml. RBC-C3b, RBC-Ic, RFER, RFIR, and NTERT were measured. Statistical analysis and correlation analysis were performed using SPSS statistical software package. Results RBC-C3b, RFER, and NTERT were lower than normal controls in patients with colorectal cancer. RBC-I and RFIR were higher than normal controls. There is a correlation between RBC-C3b, NTERT, RFER, RFIR, and RBC-Ic in colorectal cancer. Conclusion The immune function of red blood cells in colorectal cancer is low, and its determination can be used as an objective index of immune function changes in the body. It has clinical value in the diagnosis of colorectal cancer, efficacy observation, condition monitoring and prognosis judgment.