采用吸附法提取分离紫草细胞培养液中的紫草素。研究了几种吸附剂（包括无机吸附剂和吸附树脂）对紫草素的吸附与解吸。结果发现：大孔树脂ＨＤ－１效果较好，每毫升湿树脂的吸附量可达８．６９ｍｇ／ｍＬ，解吸率达９６％以上。与传统的萃取法相比，有机溶剂用量减少６０倍左右，节省动力消耗，简化操作，大大降低分离成本，有利于工业化。 The shikonin in the culture solution of comfrey was extracted by adsorption. The adsorption and desorption of shikonin by several adsorbents (including inorganic adsorbents and adsorbents) were studied. The results showed that the macroporous resin HD-1 had a good effect, and the adsorption amount of the wet resin per ml was 8.69 mg/mL, and the desorption rate was over 96%. Compared with the traditional extraction method, the amount of organic solvent is reduced by about 60 times, the power consumption is saved, the operation is simplified, the separation cost is greatly reduced, and the industrialization is facilitated.