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近10年来,喹诺酮类抗菌药以其广谱、高效、低毒、易耐受、易透过细胞外膜、使用方便以及价廉等优点在临床上得到日益广泛的应用。随着用药剂量增大,与其它药物联合应用的不断增多,安全与合理用药显得越来越重要。本文就目前药物相互作用的研究与进展作一综述。 1 与其它抗菌药物合用 1.1 氨基糖甙类 这两类药物对革兰氏阴性菌均有良好的
In the past 10 years, quinolone antibacterials have been widely used clinically due to their advantages of broad spectrum, high efficiency, low toxicity, easy tolerance, easy penetration through the outer membrane, ease of use and low cost. With the increase of dosage, it is more and more important to use drugs in combination with other drugs safely and rationally. This article reviews current research and progress on drug interactions. 1 with other antimicrobial drugs 1.1 aminoglycosides these two types of drugs have good Gram-negative bacteria