论文部分内容阅读
作者通过实验观察到,大鼠粒细胞对活的科氏中殖孔绦虫以及虫体提取物包被的鸡红细胞(CRBC)具有细胞毒活性——激发抗体依赖性细胞介导的细胞毒作用(ADCC)。进一步证实中性粒细胞对虫体的损伤力强,同时为寄生虫的免疫逃避提供了佐证。作者使用3种方法从雄性大鼠(体重250~300g)收集细胞:(1)经腹腔内感染科氏中殖孔绦虫的幼虫(四盘蚴),于感染后14、28天取细胞;(2)在第0、2、5天静脉注射0.5mg Se-
The authors experimentally observed that rat granulocytes have cytotoxic activity against live C. polycaurs and from chicken body extract-coated chicken erythrocytes (CRBCs) - to stimulate antibody-dependent cell-mediated cytotoxicity ( ADCC). It is further confirmed that neutrophils are highly damaging to parasites and provide evidence of parasite immune evasion. The authors collected cells from male rats weighing 250-300 g using three different methods: (1) intraperitoneally infecting larvae (4-cell larvae) of Mesoclasporealis spp., And seeding cells 14 and 28 days post-infection; ( 2) on the 0,2,2 days intravenously 0.5mg Se-