目的：观察ＣＴ引导下不同方法及不同大小肾囊肿硬化治疗的效果。材料与方法：对１９８例肾囊肿ＣＴ引导下行无水乙醇（９９７％）硬化治疗，其中方法Ⅰ４７例并随访４２例为抽出囊液后直接注入２５％囊液量的无水乙醇。方法Ⅱ１５１例随访７９例为抽出囊液后根据囊肿大小每次用５～３０ｍｌ不等量的无水乙醇反复多次冲洗，后留置５～３０ｍｌ不等量的无水乙醇于囊腔内。其次将囊肿分为＜５ｃｍ组１０８例（５４５％），随访６７例；５～８ｃｍ组７４例（３７３％），随访４３例；＞８ｃｍ组１６例（８．２％），随访１１例。结果：囊肿硬化治疗方法Ⅰ与方法Ⅱ疗效有差异性（Ｐ＜００５），囊肿＜５ｃｍ组与５～８ｃｍ组及＞８ｃｍ组，疗效亦有差异性（Ｐ＜０．０５）。结论：方法Ⅱ疗效优于方法Ⅰ，囊肿越小，疗效越好 Objective: To observe the effect of CT-guided different methods and different sizes of renal cyst sclerosis treatment. Materials and Methods: 198 cases of renal cyst CT guided desiccation of ethanol (99.7%) sclerosis treatment, of which 47 cases of method and follow-up of 42 cases were withdrawn cyst fluid injection directly into 25% of the volume of liquid ethanol. Method Ⅱ 151 cases were followed up for 79 cases of cyst fluid after withdrawal according to the size of the cyst each with 5 ~ 30ml different amount of ethanol repeatedly washed several times, after leaving 5 ~ 30ml unequal amount of ethanol in the cysts. Followed up were 67 cases (74.3%) in 5 ~ 8cm group, 43 cases were followed up, 16 cases (8.2%) in> 8cm group, Follow-up in 11 cases. Results: The curative effect of cyst sclerosis Ⅰ and Ⅱ were different (P <005), cyst <5cm, 5 ~ 8cm and> 8cm (P <0.05). Conclusion: The efficacy of method Ⅱ is superior to that of method Ⅰ, and the smaller the cyst, the better the curative effect