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目的:观察气血双补法在胃肠道恶性肿瘤术后化疗中的临床应用疗效。方法:将77例胃肠道恶性肿瘤患者随机分为治疗组39例和对照组38例,两组患者均采用FOLFOX6方案行第1周期化疗。治疗组在开始化疗前5d开始口服气血双补的代表方中药八珍汤加味,对照组在化疗前和化疗期间不使用任何刺激骨髓功能的药物。结果:两组骨髓抑制情况、化疗后呕吐和化疗前后精神状态比较有显著性差异(P<0.05)。结论:化疗配合气血双补,能减少化疗导致的骨髓抑制,减轻化疗引起呕吐,提高化疗后精神状态。
Objective: To observe the effect of qi and blood double-supplement method in the postoperative chemotherapy of gastrointestinal malignant tumor. Methods: Totally 77 patients with gastrointestinal cancer were randomly divided into treatment group (39 cases) and control group (38 cases). Both groups received FOLFOX6 regimen for the first cycle of chemotherapy. The treatment group began to take the representative traditional Chinese medicine Bazhen Decoction 5 d before the start of chemotherapy and the control group did not use any drugs that stimulate bone marrow function before chemotherapy and during chemotherapy. Results: There was a significant difference between the two groups in bone marrow suppression, vomiting after chemotherapy and mental state before and after chemotherapy (P <0.05). Conclusion: Chemotherapy combined with qi and blood can reduce bone marrow suppression caused by chemotherapy, reduce chemotherapy induced vomiting and improve mental state after chemotherapy.