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通过左心导管法，对４１例可疑冠心病患者进行选择性冠状动脉造影，同时检测左室舒张功能的３个指标：左室舒张末压（ＬＶＥＤＰ）、等容舒张期左室压力下降最大速率（－ｄｐ／ｄｔｍａｘ）、等容舒张期左室压力下降时间常数（Ｔｃｏｎ）。结果表明：临床上无明显心功能不全表现的冠心病患者，当冠状动脉狭窄程度≥５０％时，即可出现早期的左室舒张功能不全。随着冠状动脉狭窄程度的加重和累及血管数目的增加，左室舒张功能不全愈加重。同时可见左室舒张功能检测指标中，Ｔｃｏｎ较ＬＶＥＤＰ和－ｄｐ／ｄｔｍａｘ更为可靠和敏感。
By left heart catheterization, 41 cases of suspected coronary heart disease patients undergoing selective coronary angiography, while measuring left ventricular diastolic function of the three indicators: left ventricular end-diastolic pressure (LVEDP), isovolumic diastolic left ventricular pressure decreased the maximum rate (-dp / dtmax), left ventricular pressure decline time constant (Tcon) during isovolumic diastolic phase. The results showed that in patients with coronary heart disease without obvious clinical manifestations, early left ventricular diastolic dysfunction may occur when the degree of coronary artery stenosis is ≥50%. With the severity of coronary stenosis and the increase in the number of involved blood vessels, left ventricular diastolic dysfunction worsened. At the same time, it can be seen that Tcon is more reliable and sensitive than LVEDP and -dp / dtmax in left ventricular diastolic function.