西咪替丁可引起血催乳素过多症（雷尼替丁引起的程度较轻），并可引起男子女性型乳房及女子乳房肿胀，然而尚无证据表明法莫地丁可影响催乳素的分泌。本文报道1名法莫替丁引起血催乳素过多症和乳房肿胀患者。患者为67岁妇女，因十二指肠溃疡曾先后用西咪替丁和雷尼替丁治疗，因 Cimetidine causes hyperprolactinemia (which is less severe with ranitidine) and causes swelling in the breasts of both women and men, but there is no evidence that famotidine affects prolactin secretion. This article reports one famotidine induced hyperprolactinemia and breast swelling in patients. The patient was 67 years old and was treated with cimetidine and ranitidine because of duodenal ulcers