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梅尼埃病的耳蜗电图呈典型的明显-SP改变,但其产生机理尚不清楚。作者对一些梅尼埃病患者进行了长期随访,观察了其耳蜗电图的波动变化。受试者为24例耳蜗电图具有明显-SP改变或-SP/AP比值异常增大的梅尼埃病患者,其中12人接受内淋巴囊瓣膜移植手术,另12人采用非手术治疗。在首次耳蜗电图记录后的1～9年间,每个受试者又分别接受3～9次不等的耳蜗电图检测。结果显示,12名手术病人中,仅1人的-SP/AP比值日后发生了明显改变,自第4年,其-SP/AP比值一直保持在正常水平,其术后7个月和4.5年的听力图显示,250Hz和500Hz的纯音听力得到改善,而2kHz以上的纯声听力则进一步减退,余11人
The electrocochlear electrogram of Meniere’s disease showed typical-SP changes, but its mechanism of production is not clear. The authors conducted a long-term follow-up of some patients with Meniere’s disease and observed changes in their cochlear electrogram. The subjects were 24 Meniere’s disease with significant changes in the cochlear electrocochleogram or abnormal increase in the -SP / AP ratio, of whom 12 underwent endolymphatic balloon valvuloplasty and 12 underwent non-surgical treatment. Between the first and the 9th year after the first electrocochleography was recorded, each subject received 3 to 9 different cochlear electrograms. The results showed that only one out of 12 surgical patients had a significant change in the -SP / AP ratio in the future. Since the fourth year, the ratio of -SP / AP remained at a normal level. After 7 months and 4.5 years Audiogram showed that pure-tone audiometry at 250 Hz and 500 Hz improved, while pure-tone audiometry at 2 kHz further decreased, with more than 11