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伪石蒜碱(Pseudolycorine)是从石蒜科植物(Narcissus Tazetta、L.var ChinensisRoem或N.Papyraceus)及石蒜(lycorisRadiata Herb)提取出来的生物碱。据文献报道,该碱有抗病毒作用。潘启超等发现其可抗实验动物肿瘤。为了进一步探讨其体内过程与了解影响伪石蒜碱抗肿瘤疗效的因素,我们用~3H-伪石蒜碱在正常及带艾氏腹水癌小鼠进行了药代动力学的研究。
Pseudolycorine is an alkaloid extracted from Amaryllidaceae plants (Narcissus Tazetta, L.var Chinensis Roem or N.Papyraceus) and Lycoris Radicata Herb. According to the literature, the base has antiviral effects. Pan Qichao found that it can be resistant to experimental animal tumors. In order to further explore its in vivo process and to understand the factors that affect the antitumor efficacy of Lysine, we performed pharmacokinetic studies with ~ 3H-Lysine in normal and Ehrlich ascites carcinoma mice.