论文部分内容阅读
通过4家医院儿科病人为期1年的药物不良反应协作监测，对1856例住院病人的药物不良反应进行前瞻性观察。发现107例发生了药物不良反应，发生率为5．8％。其中A型反应79例（73．8％），B型28例（26．2％）。药物不良反应致停药者48例，需处理者31例，致死者1例。因药物不良反应致住院者27例、不良反应发生率与庄院时间，共用药物数量，疾病构成有关。小儿某些生理特征对药物不良反应发生有显著影响。
Through 4 years of pediatric patients in 4 hospitals collaborative monitoring of adverse drug reactions for 1 year, 1856 cases of hospitalized patients were prospectively observed adverse drug reactions. 107 cases found adverse drug reactions, the incidence was 5.8%. Type A reaction in 79 cases (73.8%), type B in 28 cases (26.2%). Adverse drug reactions caused discontinuation in 48 patients, need to deal with 31 cases, 1 case of lethal. Adverse reactions caused by adverse drug reactions in 27 cases of hospitalized patients, the incidence of adverse reactions and hospital time, the number of shared drugs, disease related. Some physiological characteristics in children have a significant impact on adverse drug reactions.