The single crystal of [Ba(H2O)2(C6H12O6)2Cl2] was obtained based on the phase equilibrium results. Its structure was determined by X-ray crystallographic analysis. The crystals are monoclinic and in space group C2/c with a=1.901 7(2) nm, b = 0.682 13(8) nm, c = 0.162 60(2) nm,β=96.593(2)°and V= 2.095 3(4) nm3, Z= 4, DC=1.917 g·cm-3. In its solid state, this supramolecular complex is a three-dimensional network with double layers connected by hydrogen bondings. The molecule structure of [Ba(H2O)2(C6H12O6)2Cl2] has a central barium ion that is coordinated to two water molecules, two chlorides, and four hydroxyls from the two inosi-tols. Losing the coordinating water is controlled by random nucleation and growth mechanism (n = 2/3) and 3-dimensional diffusion mechanism (n=2). The single crystal of [Ba (H2O) 2 (C6H12O6) 2Cl2] was obtained based on the phase equilibrium results. Its structure was determined by X-ray crystallographic analysis. The crystals are monoclinic and in space group C2 / c with a = 1.901 (2) nm, b = 0.682 13 (8) nm, c = 0.162 60 (2) nm, β = 96.593 (2) ° and V = 2.095 3 cm-3. In its solid state, this supramolecular complex is a three-dimensional network with double layers connected by hydrogen bondings. The molecule structure of [Ba (H2O) 2 (C6H12O6) 2Cl2] has a central barium ion that is coordinated to Two water molecules, two chlorides, and four hydroxyls from the two inosi-tols. Losing the coordinating water is controlled by random nucleation and growth mechanism (n = 2/3) and 3-dimensional diffusion mechanism (n = 2).