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目的：探讨新生儿时期轮状病毒感染的情况。方法：用酶联免疫吸附试验（ＥＬＩＳＡ）对８９例新生儿的粪便、唾液分别进行Ａ组轮状病毒（ＲＶ）检测，其中同时检测２０例母亲粪便、乳汁ＲＶ。结果：粪便轮状病毒检出率６８．５％，唾液ＲＶ检出率５３．９％。粪阳性者中无症状者达８３．６％，粪便、唾液检出率与日龄间无明显关系（Ｐ＞０．０５）；母乳喂养者粪便、唾液检出率明显低于人工喂养者（Ｐ＜０．０１或＜０．０５）。结论：新生儿时期轮状病毒感染率高，大多为无症状者，少数有腹泻者症状亦较轻。
Objective: To investigate the status of rotavirus infection during neonatal period. Methods: Seroprevalence of group A rotavirus (RV) was detected in 89 newborn infants by enzyme-linked immunosorbent assay (ELISA), including 20 cases of mother’s stool and milk RV. Results: The detection rate of stool rotavirus was 68.5% and the detection rate of saliva RV was 53.9%. There was no significant correlation between feces and saliva detection rate and age (P> 0.05). Feces and saliva detection rates in breastfeeding were significantly lower than those in artificial feeding P <0.01 or <0.05). Conclusion: The rate of rotavirus infection during neonatal period is high, most of whom are asymptomatic, and the minority have diarrhea with mild symptoms.