本品化学结构虽与烷化剂三乙撑蜜胺(癌宁、TEM)相似,但作用方式与后者不同。我院于1973年开始试制,并对其合成路线和生产工艺进行了研究。江苏省农垦局清江制药厂于1977年参加了六甲蜜胺临床药品的生产和质量标准制定的研究工作。通过药理和毒性试验以 Although the chemical structure of this product is similar to the alkylating agent triethylenemelamine (Ammonite, TEM), the mode of action is different from that of the latter. Our hospital began trial production in 1973, and its synthetic route and production process were studied. Jiangsu Province Bureau of Reclamation Qingjiang Pharmaceutical Factory in 1977 to participate in the production of altretamine melamine drugs and quality standards for the development of research. Through pharmacological and toxicological tests