研究表明，硫酸多糖体外对多聚阳离子和氧自由基损伤的人脐静脉内皮细胞有保护作用。肝素、硫酸软骨素Ａ抗多聚阳离子损伤作用比同浓度低分子肝素和甘糖酯强。肝素、硫酸软骨素Ａ、甘糖酯抗氧自由基损伤作用优于同浓度低分子肝素。结果显示硫酸多糖有保护血管内皮的作用，其作用可能与所带阴离子基团有关。 Studies have shown that sulfated polysaccharides in vitro polycations and oxygen free radicals damage human umbilical vein endothelial cells have a protective effect. Heparin, chondroitin sulfate A anti-polycation damage role than the same concentration of low molecular weight heparin and sugar esters strong. The effects of heparin, chondroitin sulfate A and glycofurol on the free radical damage were better than low molecular weight heparin at the same concentration. The results show that sulfuric acid polysaccharide has the role of vascular endothelial protection, its role may be associated with the anionic groups.