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分析３１例单纯原发性高血压（ＥＨ）、４２例高血压合并糖尿病（ＤＭ）及１０例正常对照患者的葡萄糖耐量试验（ＯＧＴＴ）、血清胰岛素（ＩＳ）、血糖水平（ＳＧ）及ＩＳ／ＳＧ，发现ＥＨ组与ＥＨ合并ＤＭ组、空腹及ＯＧＴＴ２ｈＩＳ明显高于对照组，提示ＥＨ与ＥＨ合并ＭＤ患者均存在胰岛素抵抗（ＩＳＲ）及高胰岛素血症（ＨＩＳ）。另外，ＥＨ合并ＤＭ组在ＯＧＴＴ２ｈ分泌ＩＳ及２ｈＩＳ／ＳＧ值均明显低于单纯ＥＨ组，提示ＥＨ合并ＤＭ组的胰岛素抵抗及高胰岛素血症的程度明显不如单纯ＥＨ组。本文还比较了经ＡＣＥ抑制剂（开搏通）治疗前后对两组患者胰岛素抵抗改善的影响。
The glucose tolerance test (OGTT), serum insulin (IS), blood glucose level (SG) and IS / BP of 31 patients with simple essential hypertension (EH), 42 patients with hypertension complicated with diabetes mellitus SG. It was found that fasting and OGTT2hIS in EH group and EH combined with DM group were significantly higher than those in control group, suggesting that both insulin resistance (ISR) and hyperinsulinemia (HIS) were present in both EH and EH with MD. In addition, EH combined with DM group secreted IS and 2hIS / SG values at OGTT2h were significantly lower than the EH group, suggesting that EH with DM group insulin resistance and hyperinsulinemia was significantly less than the EH group. This article also compared the impact of ACE inhibitor (Caifentong) treatment on improvement of insulin resistance in both groups before and after treatment.