lactamase相关论文
AIM: To identify the risk factors for organ failure(OF) in cholangitis with bacteriobilia.METHODS: This study included 1......
To overcome ampicillin-resistance of bacteria which is believed to attribute their endogenous β-lactamase,we designed t......
Carbapenems are potent β-lactams with activity against extended-spectrum cephalosporinases and β-lactamases. These ant......
In an effort to understand the recombination of a B2 metallo-β-lactamase(MβL),the binding of metals to apo-ImiS was st......
Design,synthesis and biological evaluation of sulfenimine cephalosporin sulfoxides as β-lactamase in
A series of sulfenimine cephalosporin sulfoxide derivatives(7a–v) were designed, synthesized and evaluated for their in......
Objective:To assess potential risk factors for diabetic foot ulcers infected with multidrug-resistant-organisms(MDROs)an......
As an important opportunistic pathogen, Pseudomonas aeruginosa (P. aeruginosa, PA) was the most prevalent bacterial path......
A unicellular cyanobacterium Synechococcus sp. strain PCC 7002 was transformedwith plasmid pQL1, on which β-lactamase g......
Class Ⅰ integron with a novel cassette array in an ESBL-producing multidrug-resistant Klebsiella pne
Objective: To analyze the molecular mechanism of integron mediated multi-resistance in an ESBL-producing K.pneumoniae NJ......
OBJECTIVE: To detect bile anaerobic bacteria and antibiotic susceptibility in 59 patients with gallstoneswho had had ch......
Analysis of the Clinical Characteristics and Antibiotics Resistance of Community-acquired Methicilli
The purpose of this investigation is to study the clinical characteristics of infections by community-acquired methicill......
Characteristics of pathogenic microorganisms found in 99 cases of conjunctivitis from the Qinghai Ti
Dear Editor,Morbidity associated with conjunctivitis is higher in developing countries,particularly among children,becau......
Severe infection with multidrug-resistant Salmonella choleraesuis in a young patient with primary sc
Massive global spread of multidrug-resistant(MDR) Salmonella spp. expressing extended-spectrum beta-lactamase(ESBL) and ......
Treatment of sepsis: What is the antibiotic choice in bacteremia due to carbapenem resistant Enterob
Sepsis is one of the major challenges of today. Although gram-positive bacteria related infections are more prevalent in......
To study the bioequivalence of Clavulanate Potassium and Amoxicillin (1:7) dispersible tablets, a randomized cross o......
Aim:To find human dopamine receptors,especially Dl-like receptor specific ago-nists from Chinese herbs as potential ant......
It is now well established that among the penicillins and cephalosporins,one of the most important mechanisms of resist......
铜绿假单胞菌能通过产生多种 β 内酰胺酶、改变细菌外膜的渗透性及各种主动泵出系统以及形成生物膜而对抗生素产生耐受性 ,本文就......
The antimicrobial susceptibility testing was performed with Kirby-Bauer disc diffusion and agar diffusion methods, and t......
Extended-spectrum β-lactamases (ESBLs) are the main cause of resistance to the third and forth-generation cephalosporin......
Surveillance on the multi-drug resistance and the β-lactamase resistance genes in Pseudomonas aerugi
In the present study,27 multi-drug resistant strains of Pseudomonas aeruginosa were isolated from clinical specimens in ......
1.Patient’s conditions:A lung cancer patient with intravenous infusionneedle retaining in vein more than one week forch......
Objective:To investigate the mechanism of carbapenem resistance and the occurrence of plasmid-mediated quinolone resista......
目的 建立反相高效液相色谱法用于同时测定他唑巴坦和头孢他啶的含量。方法 采用Zorbax 30 0SB C1 8色谱柱 ,流动相为甲醇 磷酸......
Antibacterial activities of ethanol extracts of Philippine medicinal plants against multidrug-resist
Objective: To investigate the antibacterial activities of crude ethanol extracts of 12 Philippine medicinal plants.Metho......
复发性中耳炎和治疗失败的中耳炎的细菌病因学研究很少。菌株产生β-内酰胺酶(β-lactamase)的发现使得选择性治疗中耳炎更为重要......
Comparative study on occurrence of class A and class Cβ-lactamase genes and their co-occurrence in I
Objective:To determine the occurrence of class A and class Cβ-Iactamase genes and their cooccurrence in Indian Enteroba......
产生新德里金属β-内酰胺酶-1(New Delhi metallo-β-lactamase-1,NDM-1)的耐药菌携带blaNDM-1基因,能够水解除氨曲南以外几乎所有......
The antibacterial activity of selected plants towards resistant bacteria isolated from clinical spec
Objective:To evaluate the antibacterial activity of eight plants against methicillinresistant Staphylococcus aureus(MRSA......
Aim:To investigate the oxacillin susceptibility restoration of methicillin-resistantStaphylococcus aureus (MRSA) by tar......
T4-like coliphage ΦKAZ14 virulent to pathogenic and extended spectrum β-lactamase-producing Escheric
Dear Editor,Bacteriophages(otherwise called phages)are a type of virus that infect bacteria.This viral type has found us......
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Objective: To determine the occurrence of CTX-M producing Escherichia coli(E. coli)from cattle feces in Bogor slaughterh......
慢性鼻窦炎并发的严重感染可能是致命性的。其感染为多微生物性的,包括需氧及厌氧菌属,有关各类抗生素疗效的资料极少。通过回顾性研......
The relationship between pharmacokinetics and pharmacodynamics is a key instrument to improve antimicrobial stewardship ......
OBJECTIVE To evaluate the synergistic effect of rosmarinic acid(RA)with antibiotics against Staphylococcus aureus(S.aure......
Objective:To investigate the gene related to β-lactam resistance and to confirm the mechanism about a synergy effect be......
Antibiotics have been preventing the spread of the harmful bacteria and saving many people’s lives for nearly a century......
β-内酰胺类抗生素由于低毒、高效、副作用较小 ,在临床上使用广泛 ,因此有越来越多的细菌对其耐药。细菌对其耐药主要涉及以下途......
目的调查舒巴坦敏感β-内酰胺酶(β-lactamase)的本底含量和添加状况,以期了解甘肃地区生鲜乳品的本底和添加水平。方法采集甘肃省......
目的探讨超广谱β-内酰胺酶(ESBLs)介导的耐药性在临床分离的大肠埃希菌、克雷伯菌属中的作用。方法收集耐氨苄西林的大肠埃希菌和......
近代研究表明,许多革兰氏阳性菌和阴性菌能产生β内酰胺酶(β—lactamase),这些酶能将某些β内酰胺类抗生素结构中的β内酰胺环水......
利用分光光度法研究3种由革兰氏阴性菌产生的TEM型β-内酰胺酶的动力学.以L-B作图法求取Km和Vmax.TEM-1、TEM-2对青霉素类有较强水......
以临床分离的一株肺炎克雷伯氏菌99-799株为研究对象,对其所产生的一种β-内酰胺酶编码基因的序列、亚型及基因定位进行研究.采用......
通过酵母双杂交系统从一个随机DNA片段文库中筛选到一个编码能与β-内酰胺酶结合的短肽SIPIS04-01的DNA序列,将它克隆到pGEX-4T-1......