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目的:观察中西医结合治疗黄褐斑的临床疗效。方法:435例患者随机分组:治疗组235例,口服本院自制祛斑冲剂30 g,2次/d,同时口服维生素C0.2 g,3次/d,外用0.025%的维A酸霜每晚1次;对照组200例,口服维生素E0.1g,3次/d,维生素C0.2 g,3次/d,外用0.025%的维A酸霜每晚1次。均连续治疗3个月,对治疗前后色斑面积消退情况进行对比观察。结果:治疗组痊愈132例(56.2%),总有效率为97.4%;对照组痊愈91例(45.5%),总有效率为76.5%。差异有统计学意义(P<0.05)。结论:中西医结合治疗黄褐斑疗效稳定,不易复发。
Objective: To observe the clinical curative effect of combining traditional Chinese and western medicine on melasma. Methods: A total of 435 patients were randomly divided into treatment group (235 cases) and oral ganoderma lucidum cream (30 g, twice daily). Oral vitamin C 0.2 g 3 times a day and topical 0.025% 1 times; control group of 200 cases, oral vitamin E0.1g, 3 times / d, vitamin C0.2 g, 3 times / d, topical 0.025% Victoria A acid cream once night. All patients were treated continuously for 3 months, and the contrast of the area of pigmented spots before and after treatment was observed. Results: The treatment group cured 132 cases (56.2%), the total effective rate was 97.4%; the control group recovered 91 cases (45.5%), the total effective rate was 76.5%. The difference was statistically significant (P <0.05). Conclusion: Integrative Chinese medicine treatment of melasma is stable, not easy to relapse.