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目的探讨丹红联合牛磺酸治疗病毒性心肌炎的临床疗效。方法104例病毒性心肌炎患者按随机数字法分成对照组1、2组和治疗组各52例,对照1组予常规治疗,对照2组在此治疗基础上加用牛磺酸,治疗组在此治疗基础上加用丹红注射液和牛磺酸,进行临床疗效比较。结果与对照组相比,治疗组主要症状及体征改善情况明显,治疗组治疗后血清肌酸磷酸激酶(CPK)、天冬氨酸转氨酶(AST)、肌酸激酶同工酶(CK-MB)及血清乳酸脱氢酶(LDH)较治疗前明显降低,差异有统计学意义(P<0.05),而对照组CPK、AST、LDH、CK-MB治疗前后比较差异均无统计学意义(P>0.05),治疗组总有效率明显高于对照组,差异有统计学意义(P<0.05)。结论丹红注射液联合牛磺酸对病毒性心肌炎具有良好的治疗作用。
Objective To investigate the clinical efficacy of Danhong combined with taurine in the treatment of viral myocarditis. Methods A total of 104 patients with viral myocarditis were randomly divided into two groups according to random number method: control group (group 1) and group (52 patients), and control group (group 1) received routine treatment. Control group (group 2) On the basis of treatment with Danhong injection and taurine, the clinical efficacy comparison. Results Compared with the control group, the improvement of the main symptoms and signs of the treatment group was obvious. Serum levels of creatine phosphokinase (CPK), aspartate aminotransferase (AST), creatine kinase MB (CK-MB) And serum lactate dehydrogenase (LDH) were significantly lower than before treatment, the difference was statistically significant (P <0.05), while the control group CPK, AST, LDH, CK-MB before and after treatment were no significant difference (P> 0.05). The total effective rate in the treatment group was significantly higher than that in the control group, with significant difference (P <0.05). Conclusion Danhong injection combined with taurine has a good therapeutic effect on viral myocarditis.