AIM: To study the effects of concentrated liquor from male zooid of Antheraea pernyi on immunological mice. METHODS: For each experiment, 40 mice were randomly divided into normal saline group (control group) and three tested groups that were administered different dosages of concentrated liquor from male zooid of A. pernyi and food for 15 d. The typical FSR and HC50 value, rnonocyte-phagocytic exponent Kand emendated monocyte-phagocytic exponent a were determined and calculated respectively. RESULTS: After 24 and 48 h, the FSR values of the three tested groups improved significantly in comparison to the control group by variance analysis. The HC50 values showed a significant difference between the high dosage group and the control group, as well as between the high dosage group and other two tested groups. The nronocyte-phagocytic exponent Kand emendated exponent a showed rising tendencies, but no significant differences were found by variance analysis. CONCLUSION: The concentrated liquor from male zooid of A. pernyi can significantly enhance cellular and humoral immune function in mice, but has no distinct influence on the monocyte-phagocytic system in mice. AIM: To study the effects of concentrated liquor from male zooid of Antheraea pernyi on immunological mice. METHODS: Each experiment, 40 mice were randomly divided into normal saline group (control group) and three tested groups that were administered different dosages of concentrated liquor from male zooid of A. pernyi and food for 15 d. The typical FSR and HC50 value, rnonocyte-phagocytic exponent Kand emendated monocyte-phagocytic exponent a were determined and calculated respectively. RESULTS: After 24 and 48 h, the FSR values ​​of the three tested groups improved significantly in comparison to the control group by variance analysis. The HC50 values ​​showed a significant difference between the high dosage group and the control group, as well as between the high dosage group and the other two tested groups. The nronocyte-phagocytic exponent Kand emendated exponent a showed rising tendencies, but no significant differences were found by variance analysis. CONCLUSION: The concentrated li quor from male zooid of A. pernyi can significantly enhance cellular and humoral immune function in mice, but has no distinct influence on the monocyte-phagocytic system in mice.