论文部分内容阅读
目的:研究鳞状细胞癌抗原(SCCAg)在宫颈癌及癌前病变中的表达和意义。方法:分析宫颈上皮内瘤变(CIN)组368例、宫颈癌组84例的SCCAg值与患者不同临床分期、分化程度等病理参数之间的关系。结果:SCCAg在宫颈癌前病变及宫颈癌早期已有变化,与临床FIGO分期、分化程度、肿瘤体积的增大及淋巴结转移呈正相关。结论:SCCAg是宫颈癌的重要临床肿瘤标志物,较高的血清SCCAg值可能意味着肿瘤恶性程度越高,为患者的辅助诊断、病情估计提供全面的指导信息。
Objective: To study the expression and significance of squamous cell carcinoma antigen (SCCAg) in cervical cancer and precancerous lesions. Methods: The relationship between SCCAg values in 368 cases of cervical intraepithelial neoplasia (CIN) group and 84 cases of cervical cancer group and pathological parameters such as clinical stage, differentiation degree and so on were analyzed. Results: The changes of SCCAg in cervical precancerous lesions and early stage of cervical cancer have a positive correlation with clinical FIGO stage, differentiation degree, tumor volume and lymph node metastasis. Conclusion: SCCAg is an important clinical tumor marker of cervical cancer. The higher serum SCCAg value may indicate the higher degree of tumor malignancy, which will provide comprehensive guidance for the diagnosis and prognosis of patients.