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在多种呼吸道疾病中常观察到粘膜纤毛缺陷,有人认为异常纤毛的存在可能与疾病有关。作者对慢性鼻窦炎患者纤毛缺陷的频度及特征进行了研究。共34个上颁窦粘膜组织标本,取自27个慢性鼻窦炎病人(男17,女11),年龄为10～79岁。另对12例一般鼻窦炎及18个增殖型鼻窦炎标本及4个正常人标本作了对比研究。用电子显微镜观察,放大18000倍,观察大约500个纤毛横切面,纤毛缺陷以半定量法进行估价。12个病人测试带有染色指示的纤毛运输能力来评价其生理功能,令病人平卧,在鼻窦镜下将0.5ml 染料滴于鼻窦后壁,观察染料向开口处移动。临床无症状的4例正常鼻窦其移动时
Mucosal cilia defects are often observed in a variety of respiratory diseases, and it is thought that the presence of abnormal cilia may be related to the disease. The authors studied the frequency and features of ciliary defects in patients with chronic sinusitis. A total of 34 sinus mucosa specimens were issued, taken from 27 patients with chronic sinusitis (male 17, female 11), aged 10 to 79 years. Another 12 cases of general sinusitis and 18 specimens of proliferative sinusitis and 4 normal subjects were compared. Observed with an electron microscope, magnified 18000 times, observed about 500 cilia cross-section, cilia defects evaluated by semi-quantitative method. Twelve patients were tested for cilia transportability with staining indications to assess their physiological function, allowing the patient to lie flat and 0.5 ml of dye was dropped on the posterior wall of the sinuses under a sinusoscope to observe the movement of the dye towards the opening. Clinical asymptomatic 4 cases of normal sinus movement