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目的:观察雌孕激素序贯治疗再次清宫术后宫腔残留的临床疗效。方法:60例再次清宫术后仍有宫腔残留的患者随机分为观察组(30例)和对照组(30例),观察组口服戊酸雌二醇片及醋酸甲羟孕酮片,对照组在清宫术后口服新生化颗粒,疗程均为21 d。比较两组患者的人绒毛膜促性腺激素(β-human chorionic gonadotropin,β-HCG)水平、阴道流血停止时间及转经时间,并进行疗效评价。结果:治疗后,观察组血清β-HCG降低差值,阴道流血停止时间及转经时间等均低于对照组(P<0.05或P<0.01)。观察组治愈率为90.00%,对照组治愈率为93.33%,两组比较差异无统计学意义(P>0.05)。结论:雌孕激素序贯治疗可改善患者临床症状,促进子宫功能修复,值得临床推广。
Objective: To observe the clinical efficacy of estrogen and progesterone sequential treatment of residual uterine cavity after curettage. Methods: Sixty patients with residual uterine cavity after radical hysteroscopic surgery were randomly divided into observation group (30 cases) and control group (30 cases). The observation group was given estradiol valerate tablets and medroxyprogesterone acetate tablets Group after oral administration of new biochemical particles in the Qing, the treatment was 21 d. The levels of β-human chorionic gonadotropin (β-HCG), vaginal bleeding time and transit time were compared between the two groups. The curative effect was evaluated. Results: After treatment, the differences of serum β-HCG, vaginal bleeding stop time and transit time in the observation group were lower than those in the control group (P <0.05 or P <0.01). The cure rate of the observation group was 90.00%, and the cure rate of the control group was 93.33%. There was no significant difference between the two groups (P> 0.05). Conclusion: The sequential treatment of estrogen and progesterone can improve the clinical symptoms of patients and promote uterine function repair, worthy of clinical promotion.