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慢性髓细胞白血病(CML)的病程各不相同。多年来,许多作者曾提出临床有用的预后标准,但所描述的多数特征均为疾病进展的表现,这些特征用于分期标准更适合。新近有人尝试提出能够预测患者仍处于稳定阶段(疾病的良性期)的预后标准,但未能取得一致意见。分期习惯上将CML分为3期,即慢性期,加速期和急变期。这些分期的定义至今未能统一。慢性期此期病情稳定可长达10-20年。各系细胞起源于成熟且功能基本正常的肿瘤
Chronic myeloid leukemia (CML) varies in duration. Over the years, many authors have proposed clinically useful prognostic criteria, but most of the described features are indicative of disease progression, and these characteristics are more appropriate for staging criteria. There have been recent attempts to come up with prognostic criteria that predict that the patient is still in a stable phase (the benign phase of the disease) but have not been able to agree. Staging CML will be divided into three phases, namely, chronic phase, accelerated phase and blastic phase. The definition of these stages has so far failed to unify. Chronic period of stable disease can be as long as 10-20 years. The Department of cells originated in mature and basically normal function of the tumor