肺结核患者白细胞介素-2受体测定结果比较

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目的:测定白细胞介素-2受体(sIL.2R)含量,为肺结核的鉴别诊断及判断预后提供帮助。方法:应用ELISA双抗夹心法对肺结核。肺癌、急性肺炎的血清和购水进行SIL-2R含量测定。结果:(1)肺结核进展期与肺结核稳定期差异有显著意义(t=2.963,P<0.01)。(2)肺结核复治组sIL-2R含量高于初治组,两者间差异有显著意义(t=2.305,P<O.05)。(3)肺结核进展期、肺癌、肺炎患者sIL-2R含量均高于正常人,肺结核进展期与肺癌sIL-2R含量间差异有显著意义(t=3.122,P<0.01)。(4)进展期肺结核血清sIL-2R含量与X线胸片范围和痰苗比较:波及4个肺野以上组sIL-2R含量最高,涉及1个肺野含量最低。瘦菌阳性组与痰菌阴性组sIL-2R含量,两组差异不显著。(5)进展期肺结核疫苗转阴和/或购片病变改善,其血清sIL-2R含量下降,胸片未改善和痰苗持续阳性者,sIL-2R含量不降低,反而呈增高趋势。(6)结核胸水与肺癌胸水sIL-2R含量,两者比较差异有显著意义(t=2.772,P<0.05)。结论:测定肺结核患者血清sIL-2R含量,有助于对进展期肺结核疾病活动性及疗效的判断。 Objective: To determine the content of interleukin-2 receptor (sIL.2R), and to provide help for the differential diagnosis and prognosis of pulmonary tuberculosis. Methods: ELISA double-antibody sandwich method of tuberculosis. Lung cancer, serums from acute pneumonia and water purchase for SIL-2R determination. Results: (1) The difference between tuberculosis progression and tuberculosis stability was significant (t = 2.963, P <0.01). (2) The content of sIL-2R in tuberculosis retreatment group was higher than that in naive group, the difference was significant (t = 2.305, P <0.05). (3) The levels of sIL-2R in patients with lung cancer and pulmonary tuberculosis were significantly higher than those in controls (t = 3.122, P <0.01). (4) The content of sIL-2R in advanced pulmonary tuberculosis was significantly higher than that of X-ray and sputum in four lung fields. Leptospirosis positive group and sputum negative group sIL-2R content, the two groups showed no significant difference. (5) The incidence of sIL-2R in advanced pulmonary tuberculosis vaccine was negative, and / or the lesions of purchased tablets were improved. The serum sIL-2R level was decreased. (6) The contents of sIL-2R in tuberculous pleural effusion and lung cancer pleural effusion were significantly different (t = 2.772, P <0.05). Conclusion: Determination of serum sIL-2R levels in patients with tuberculosis, contribute to the judgment of activity and efficacy of advanced pulmonary tuberculosis.
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