由于与一种罕见的遗传性疾病相关的基因的发现,科学家们有望开始解决至今尚属未知的动脉粥样硬化和胆固醇代谢。最近,3个独立的研究小组报告说他们在丹吉尔病(TD)中发现了突变的基因,TD是一种罕见的隐性遗传性疾病,以橙色扁桃体、周围神经病和几乎完全缺乏高密度脂蛋白(HDL)胆固醇为特征。 Due to the discovery of genes associated with a rare genetic disease, scientists are expected to begin to address so far unknown atherosclerosis and cholesterol metabolism. Recently, three independent research groups reported that they found a mutated gene in Tangier disease (TD), a rare recessive inherited disease with orange tonsils, peripheral neuropathy and almost complete absence of high-density lipids Protein (HDL) cholesterol is characterized.