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目的比较放疗、介入化疗同期应用与单纯常规放射治疗晚期宫颈鳞癌的疗效。方法子宫颈鳞癌常规外放疗10~20Gy时,辅以介入化疗的晚期宫颈癌12例与同期接受单纯常规放疗的晚期宫颈癌20例做比较。比较两组病例肿瘤缩小情况、毒性反应、3年复发及死亡率。结果治疗组(放疗、介入化疗同期应用组)肿瘤缩小明显优于对照组(单纯常规放疗组),毒性反应两组病人均能耐受,平均治疗天数治疗组为69天,对照组为67天,无明显差别。结论放疗同期介入化疗较单纯常规放疗者肿瘤缩小明显,Ⅲb期病人治疗组3年生存率高于对照组,治疗组副反应可以耐受,平均治疗天数两组无明显差别。
Objective To compare the curative effects of concurrent radiotherapy, simultaneous interventional chemotherapy and conventional radiotherapy for advanced cervical squamous cell carcinoma. Methods Conventional external radiotherapy of cervical squamous carcinoma 10 ~ 20Gy, adjuvant chemotherapy with advanced cervical cancer in 12 cases compared with the same period received conventional radiotherapy for advanced cervical cancer in 20 cases were compared. Tumor shrinkage, toxicity, 3-year relapse and mortality were compared between the two groups. Results Compared with the control group (conventional radiotherapy group), tumor shrinkage in the treatment group (radiotherapy and interventional chemotherapy group) was significantly better than that in the control group. The patients in the two groups were able to tolerate the treatment for an average of 69 days in the treatment group and 67 days in the control group , No significant difference. Conclusions Compared with conventional radiotherapy, the 3-year survival rate of Ⅲb patients is higher than that of control group. The side effects of the treatment group can be tolerated, and the average treatment days have no significant difference between the two groups.