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目的探讨血清βHCG、孕酮及雌二醇分别和协同对宫外孕诊断的临床意义。方法选取于2014年1月~2015年1来院诊断的宫外孕患者10例作为观察组,选择同期来院诊断的正常宫内早孕妇女200例作为对照组,采用电化学发光法检测2组患者的血清βHCG、孕酮及雌二醇,经t检验、卡方检验,评价血清βHCG、孕酮及雌二醇对宫外孕的诊断意义。结果组间βHCG、孕酮比较差异均有统计学意义(P<0.05),组间雌二醇比较无统计学意义(P>0.05);βHCG协同孕酮的敏感度、特异度及准确度均高于βHCG、孕酮,差异有统计学意义(P<0.05)。结论血清βHCG对宫外孕诊断具有一定的敏感性和特异性,血清βHCG与孕酮协同,可进一步提高其敏感性及特异性。
Objective To investigate the clinical significance of serum βHCG, progesterone and estradiol in the diagnosis of ectopic pregnancy respectively. Methods From January 2014 to January 2015, 10 cases of ectopic pregnancy diagnosed in our hospital from January 2014 to January 2015 were selected as the observation group, and 200 cases of normal intrauterine pregnancy in the same period were selected as the control group. The serum βHCG , Progesterone and estradiol. The t-test and Chi-square test were used to evaluate the diagnostic value of serum βHCG, progesterone and estradiol in ectopic pregnancy. Results There were significant differences in βHCG and progesterone between the two groups (P <0.05), but there was no significant difference between the two groups (P> 0.05). The sensitivity, specificity and accuracy of βHCG and progesterone Higher than βHCG, progesterone, the difference was statistically significant (P <0.05). Conclusion Serum βHCG has certain sensitivity and specificity for the diagnosis of ectopic pregnancy. Serum βHCG synergizes with progesterone to further improve its sensitivity and specificity.