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本文比较了妇血宁不同条件下提取物和不同分子量组分的药理活性。妇血宁透析内液有促凝和兴奋子宫作用。乙醇提取物F_Ⅰ,F_Ⅲ促凝、兴奋子宫和抗炎作用较强,碱提取的F_Ⅱ失去促凝作用。凝胶层析分离小分子量的F_2,F_3促凝抗炎作用强,F_2抑制子宫收缩,F_1,F_3则兴奋子宫,分子量较大的F_1无抗炎活性。
This article compares the pharmacological activities of extracts and different molecular weight fractions under different conditions of FZ blood. Women’s blood dialysis fluid has procoagulant and excitatory uterus. Ethanol extracts F_I, F_III are pro-coagulant, excitatory to the uterus, and have strong anti-inflammatory effects, and the alkali-extracted F_II loses its pro-coagulant effect. Gel chromatography was used to separate small molecular weight F_2. F_3 had a strong pro-coagulant and anti-inflammatory effect, F_2 inhibited uterine contraction, and F_1 and F_3 excitated the uterus. F_1, which has a large molecular weight, had no anti-inflammatory activity.