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本文作者用诊断剂量的超声波辐照活体家兔肝脏，喂养３ｄ致死后取材，经处理后用电子显微镜观察其超微结构的变化情况。实验结果表明超声波辐照２０ｍｉｎ的家兔肝脏的超檄结构无明显变化，而辐照３０ｍｉｎ及６０ｍｉｎ的家兔肝脏，除细胞质内粗面内质网有程度不同的扩张外，肝组织及肝细胞的其它结构均无明显改变。由于热效应与辐照时间有关，而本实验辐照３０ｍｉｎ及６０ｍｉｎ的家兔肝脏的超微结构的变化是相同的。且本实验所用超声强度小而不致引起机械效应。因此作者认为本实验出现的兔肝细胞粗面内质网扩张的现象不会是热效应和机械效应引起，而只可能是空化效应所致，这说明诊断超声可能在动物组织中引起空化效应。
The author of this study used a diagnostic dose of ultrasound to irradiate the liver of a living rabbit, which was taken after death for 3 days. The ultrastructure of the rabbit liver was observed by electron microscopy. The experimental results showed that there was no significant change in the ultrastructure of rabbit liver after ultrasonic irradiation for 20 min. However, in the rabbit liver irradiated for 30 min and 60 min, in addition to varying degrees of expansion of the rough endoplasmic reticulum in the cytoplasm, the liver tissues and hepatocytes Other structures have not changed significantly. Due to the thermal effects and irradiation time, and the experimental irradiation 30min and 60min rabbit liver ultrastructure changes are the same. And the intensity of ultrasound used in this experiment is small and does not cause mechanical effects. Therefore, the authors believe that the experimental phenomenon of rabbit liver cells rough endoplasmic reticulum expansion phenomenon will not be caused by thermal and mechanical effects, but only due to cavitation effect, indicating that diagnostic ultrasound may cause cavitation in animal tissues .