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用彩色多普勒血流显象（ＣＤＦＩ）和脉冲多普勒超声心动图（ＰＤＥ）检测２６例肾功能正常的非胰岛素依赖型糖尿病病人及２０例正常人的双侧肾动脉血流，以探讨糖尿病肾病血流动力学改变。糖尿病病人与正常人对照，肾动脉内径增宽（Ｐ＜０．０１），血流量增加（Ｐ＜０．０１），搏动指数及阻力指数降低（Ｐ＜０．０５）。结果表明，糖尿病临床肾病前期呈高灌注、低阻力改变。提示ＣＤＦＩ和ＰＤＥ可为临床早期发现糖尿病肾病提供一项简便易行的非创伤性检测方法。
Twenty-six patients with non-insulin-dependent diabetic patients with normal renal function and 20 normal subjects with bilateral renal artery blood flow were examined by color Doppler flow imaging (CDFI) and pulsed-wave Doppler echocardiography (PDE) To investigate the hemodynamic changes of diabetic nephropathy. Diabetic patients and normal controls, renal artery diameter widened (P <0.01), blood flow increased (P <0.01), pulsatility index and resistance index decreased (P <0.05). The results showed that early diabetic nephropathy was perfusion, low resistance changes. It is suggested that CDFI and PDE can provide an easy and non-invasive method for the early detection of diabetic nephropathy in clinic.