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国际上用15甲基PGF2α甲酯阴道栓剂终止早孕已有报道。我院自1983年11月～1985年6月底将我国合成的d1-15甲基PGF2α甲酯(简称PG05),用于抗早孕进行研究,先后使用5种不同配方。现将效果较好的5号方对186例早、中孕妇女终止妊娠的临床观察分析如下。 对象和方法 一、对象选择 健康妊娠妇女,经妇科检查,乳胶妊娠反应试验或血HCG确诊为妊娠者,在无禁忌情况下,不计年龄、孕产次,均收入院观察。孕≤8周者97例,>8～12周者67例,>12周者22例,共186例。其中剖腹产史者19例,有1例为两次剖腹产史。双阴道、双宫颈、双子宫畸形者11例,足月产后半年内又孕者43例,人流术后3个月内又孕者27例,共100例,占53.8％.
International termination of early pregnancy with 15 methyl PGF2α methyl ester vaginal suppository has been reported. Our hospital from November 1983 to the end of June 1985 will be China’s synthetic d1-15 methyl PGF2α methyl ester (referred to as PG05), for anti-early pregnancy study, has used five different formulations. Now the better effect on the 5th side of 186 cases of early pregnancy, pregnant women, the clinical observation of the termination of pregnancy are as follows. Subjects and methods First, the object Select a healthy pregnant women, gynecological examination, latex pregnancy test or blood HCG diagnosis of pregnancy, in the absence of contraindications, regardless of age, pregnancy and childbirth, were admitted to the hospital observation. 97 cases of pregnancy ≤ 8 weeks, 67 cases of> 8 to 12 weeks,> 12 weeks in 22 cases, a total of 186 cases. Including caesarean section in 19 cases, 1 case of two caesarean section. There were 11 cases of double vagina, double cervix and double uterus malformations, 43 cases of pregnant women within half a year of full-term postpartum and 27 cases of pregnant pregnancies within 3 months after abortion, a total of 100 cases (53.8%).