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To explore the application value of hemodialysis-related nursing sensitive indicators in improving the quality of hemodialysis.Methods Totally 40 outpatients undergoing dialysis treatment from January 2016 to December 2016 served as observation group.Another 40 outpatients who received dialysis from January 2015 to December 2015were selected as control group.Patients in control group received routine nursing and health education on hemodialysis,and those in observation group were given interventions based on nursing sensitive indicators.The hemodialysis-related nursing sensitive indicators and satisfactory degree of patients on nursing service were compared between two groups.Results Observation group had a better outcome of hemodialysis nursing sensitive indicators compared with control group (observation group:Kt/V [1.30 ±0.06],Hib [115.0 ±4.8] g/L,serum Ca [2.31 ±0.06] mmoL/L,serum P [1.75 ±0.18]mmoL/L,product of Ca and P [30.95 ± 0.58] mg2/dl,PTH [305 ± 65] pg/mL.control group:Kt/V [1.18 ±0.07],Hb [99.0 ±5.2] g/L,serum Ca[2.52 ±0.07] mmoL/L,serum P [2.07 ± 0.21] mmoL/L,product of Ca and P [39.75 ±0.74] mg2/dl,PTH [420 ± 84]pg/mL.P ＜ 0.05 respectively.) The satisfactory degree of patients on nursing service was 97.5％ (39/40) in observation group and 80.0％ (32/40) in the control group,with a significant difference (P ＜ 0.05).Conclusion Hemodialysis-related nursing sensitive indicators provide a scientific basis for nursing quality improvement in patients with hemodialysis,and also play a certain role in promoting high quality nursing service.