目的探讨宫内感染与非感染性发热的高危因素、临床特征及对母婴预后的影响。方法选取待产过程中体温超过37.5℃产妇191例进行回顾性分析,其中胎盘病理检查为绒毛膜羊膜炎者101例,定义为感染组;另90例为对照组。比较两组病例胎膜早破率及胎膜破裂时长、产程时长、体温、剖宫产以及新生儿体重、感染、窒息和产褥病率等。结果感染组胎膜破裂时长、产程时长、血象异常率、剖宫产率以及新生儿体重、新生儿感染率高于对照组(P<0.05或P<0.01);但两组病例其他资料无统计学差异。结论胎膜破裂、产程时长、新生儿体重与宫内感染相关,感染性发热临床上要综合分析、动态监测,保证母婴安全。 Objective To investigate the risk factors of intrauterine infection and noninfectious fever, clinical characteristics and prognosis of maternal and infant. Methods Totally 191 pregnant women whose body temperature exceeded 37.5 ℃ during the course of waiting-to-be produced were retrospectively analyzed. Among them, 101 cases of chorioamnionitis were identified as infection group and 90 cases were control group. Premature rupture of membranes and duration of rupture of membranes, duration of labor, body temperature, cesarean section and neonatal weight, infection, asphyxia and puerperal morbidity were compared between the two groups. Results The duration of labor, length of labor, abnormal blood rate, cesarean section rate, neonatal birth weight and neonatal infection rate in infection group were higher than those in control group (P <0.05 or P <0.01). However, no other data were found in the two groups Differences Conclusion The rupture of fetal membranes, labor duration, neonatal weight and intrauterine infection related to infectious fever should be comprehensive clinical analysis, dynamic monitoring to ensure the safety of mother and child.